Abstract
The modern science mainly treats the biochemical basis of sequencing in bio-macromolecules and processes in biochemistry. One can ask weather the language of biochemistry is the adequate scientific language to explain the phenomenon in that science. Is there maybe some other language, out of biochemistry, that determines how the biochemical processes will function and what the structure and organization of life systems will be? The research results provide some answers to these questions. They reveal to us that the process of sequencing in bio-macromolecules is conditioned and determined not only through biochemical, but also through cybernetic and information principles.
Keywords
•HLA-B 3801• B 3905 B16 • B 39011• bb 6701• bb 9022 • b 1401 • episodic evolution • HLA-B Code
Methods The allele fequencises used by the modern science are characterized and determined by principles of biochemistry. However, if in those alleles, instead of the ATGC nucleotides we put the number of atomic numbers, we will get the HLA-B code characterized and determined by programmatic and information principles. Therefore, biochemistry can be explained through a phenomenon out of biochemistry. Particularly interesting results we will get when determining numeric values for the information content of atoms and molecules. We will then find out that those values express physical and chemical characteristics of molecules. For example: in a DNA molecule, the polynucleotide chains are connected through an exact cyber-information connections. In those molecules there are also mathematical matrixes of DNA, represented by the number of atoms of four ATCG bases. These matrixes determine the positioning of nucleotides in that molecule. With this, the biological particularities of DNA are determined. Similar mathematical matrixes determine the positioning of nucleotides in the RNA molecule. In the amino acid proteins, they are interconnected into the respective mathematical chains. In those chains are also matrixes where particular mathematical principles apply, the principles that determine the positioning of each amino acid in the chain.
The herewith discussed research results show that the process of sequencing OF NUCLEOTIDES in alleles frequencies is conditioned and determined not only through biochemical, but also through cybernetic information principles.
We would particularly like to stress here that the genetic, as well as biochemical information in a broader sense of the word, is determined and characterized by very complex cybernetic and information principles. The constantans in those principles are: the number of atoms and molecules, atomic numbers, atomic weight, physical and chemical parameters, even and odd values, codes and analogue codes, standard deviations, frequencies, primary and secondary values, and many other things. How functioning of biochemistry is determined through cybernetic information principles, will be discussed further in this text.
The Atomic HLA-B code
Atomic numbers:
A = 70; T = 66; G = 78; C = 58;
HLA-B - b 3801
TTGGCCGCCCTTGCTAAGAGAGAAGGGACACAT
TGCAAACAATAAGTGCTCCCCTCAGGACGGCT
ATTCGAGCTCTGAACGTGCCGTACCCGAGGGTC
Atomic numbers:
First we made a digital image of the ATCG nucleotide:
66,66,78,78,58,58,78,58,58,58,66,66,78,58,66,70,70,78,70,78,
70,78,70,70,78,78,78,70,58,70,58,70,66,66 78,58,70,70,70,58,
70,70,66,70,70,78,66,78,58,66,58,58,58,58,66,58, 70,78,78,70,
58,78,78,58,66,70,66,66,58,78,70,78,58,66,58,66,78,70,70,58,
78,66,78,58, 58,78,66,70,58,58,58,78,70,78,78,78,66,58
Decoding scheme:
[(A x B ) : (A : 2)] = R;
A > A1, A2
A1
!
TTGGCCGCCCTTGCTAAGAGAGA
R
AGGGACACATTGCAAACAATAAGTGC
TCCCCTCAGGACGGCTATTCGAGCTC
A2
TGAACGTGCCGTACCCGAGGGTC
A1 = 1574;
A2 = 1574;
R = 3516;
A1
66,66,78,78,58,58,78,58,58,58,66,66,78,58,66,70,70,78,70,78,70,78,70,
R
70,78,78,78,70,58,70,58,70,66,66,78,58,70,70,70,58,70,70,66,
70,70,78,66, 78,58,66,58,58,58,58,66,58, 70,78,78,70,58,78,78,
58,66,70,66,66,58,78,70,78,58,66,58,
A2
66,78,70,70,58,78,66,78,58, 58,78,66,70,58,58,58,78,70,78,78,78,66,58
A1
1574
I
66,66,78,78,58,58,78,58,58,58,66,66,78,58,66,70,70,78,70,78,70,78,70,
R
I
3516
I
70,78,78,78,70,58,70,58,70,66,66,78,58,70,70,70,58,70,70,66,70,70,78,66, 78,58,66,58,58,58,58,66,58, 70,78,78,70,58,78,78,58,66,70,66,66,58,78,70,78,58,66,58,
A2
I
1574
I
66,78,70,70,58,78,66,78,58, 58,78,66,70,58,58,58,78,70,78,78,78,66,58
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